Medication IG DE
1.0.0-ballot1 - 1.0.0

This page is part of the Medication IG DE (vballot1: Releases Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. This is the current published version. For a full list of available versions, see the Directory of published versions

Data Type Profile: DosageDE - Detailed Descriptions

Draft as of 2025-07-11

Definitions for the DosageDE data type profile.

Guidance on how to interpret the contents of this table can be foundhere

0. Dosage
Definition

Indicates how the medication is/was taken or should be taken by the patient.

ShortHow the medication is/was taken or should be taken
Control0..*
This element is affected by the following invariants: ele-1
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
2. Dosage.extension:generatedDosageInstructions
Slice NamegeneratedDosageInstructions
Definition

Diese Extension enthält die automatisch generierte textuelle Dosierungsanweisung, die auf Basis der bereitgestellten strukturierten Dosierungsinformationen erstellt wurde.

ShortMaschinell erzeugte Dosieranweisung
Control0..1
This element is affected by the following invariants: ele-1
TypeExtension(Maschinell erzeugte Dosieranweisung) (Complex Extension)
Must Supporttrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
4. Dosage.modifierExtension
Definition

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

ShortExtensions that cannot be ignored even if unrecognized
Comments

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Control0..*
This element is affected by the following invariants: ele-1
TypeExtension
Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summarytrue
Requirements

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Alternate Namesextensions, user content, modifiers
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
6. Dosage.text
Definition

Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Tablette bei Bedarf'. Als Quelle dient hier ausschließlich der Arzt oder Apotheker


Free text dosage instructions e.g. SIG.

ShortFreitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Tablette bei Bedarf'Free text dosage instructions e.g. SIG
Comments

Die Freitextdosierung sollte nur angegeben werden, wenn aufgrund der Komplexität keine strukturierte Dosierung möglich ist, um widersprüchliche Anweisungen zu vermeiden.


Note that FHIR strings SHALL NOT exceed 1MB in size

Control0..1
This element is affected by the following invariants: ele-1
Typestring
Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
Must Supporttrue
Summarytrue
Requirements

Free text dosage instructions can be used for cases where the instructions are too complex to code. The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated. If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing. Additional information about administration or preparation of the medication should be included as text.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
8. Dosage.timing
Definition

Wann das Medikament verabreicht werden soll.


When medication should be administered.

ShortWann das Medikament verabreicht werden sollWhen medication should be administered
Comments

Um widersprüchliche Anweisungen zu vermeiden, ist entweder Dosage.timing oder Dosage.text zu befüllen. Falls eine strukturierte Dosierung als Text abgebildet werden soll ist dafür die GeneratedDosageInstructions Extension zu verwenden.


This attribute might not always be populated while the Dosage.text is expected to be populated. If both are populated, then the Dosage.text should reflect the content of the Dosage.timing.

Control0..1
This element is affected by the following invariants: ele-1
TypeTiming(Zeitmuster für deutschlandweite Dosierungen)
Must Supporttrue
Summarytrue
Requirements

The timing schedule for giving the medication to the patient. This data type allows many different expressions. For example: "Every 8 hours"; "Three times a day"; "1/2 an hour before breakfast for 10 days from 23-Dec 2011:"; "15 Oct 2013, 17 Oct 2013 and 1 Nov 2013". Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
10. Dosage.doseAndRate
Definition

Die verabreichte Menge des Medikaments.


The amount of medication administered.

ShortMenge des verabreichten MedikamentsAmount of medication administered
Control0..*
This element is affected by the following invariants: ele-1
TypeElement
Must Supporttrue
Summarytrue
Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
12. Dosage.doseAndRate.dose[x]
Definition

Amount of medication per dose.

ShortAmount of medication per dose
Comments

Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.

Control0..1
This element is affected by the following invariants: ele-1
TypeChoice of: Range, Quantity(SimpleQuantity)
[x] NoteSeeChoice of Data Typesfor further information about how to use [x]
Summarytrue
Requirements

The amount of therapeutic or other substance given at one administration event.

Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
SlicingThis element introduces a set of slices on Dosage.doseAndRate.dose[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
  • type @ $this
  • 14. Dosage.doseAndRate.dose[x]:doseQuantity
    Slice NamedoseQuantity
    Definition

    Menge des Medikaments pro Dosis.


    Amount of medication per dose.

    ShortMenge des Medikaments pro DosisAmount of medication per dose
    Comments

    Beachten Sie, dass dies die Menge des angegebenen Medikaments angibt, nicht die Menge für die einzelnen Wirkstoffe. Jede Wirkstoffmenge kann in der Medication-Ressource kommuniziert werden. Zum Beispiel, wenn man angeben möchte, dass eine Tablette 375 mg enthält und die Dosis eine Tablette beträgt, kann man die Medication-Ressource verwenden, um zu dokumentieren, dass die Tablette aus 375 mg des Wirkstoffs XYZ besteht. Alternativ, wenn die Dosis 375 mg beträgt, muss man möglicherweise nur angeben, dass es sich um eine Tablette handelt. Bei einer Infusion wie Dopamin, bei der 400 mg Dopamin in 500 ml einer Infusionslösung gemischt werden, würde dies alles in der Medication-Ressource kommuniziert werden. Wenn die Verabreichung nicht als sofortig vorgesehen ist (Rate ist vorhanden oder Timing hat eine Dauer), kann dies angegeben werden, um die Gesamtmenge anzugeben, die über den im Zeitplan angegebenen Zeitraum verabreicht werden soll, z. B. 500 ml in der Dosis, wobei Timing verwendet wird, um anzugeben, dass dies über 4 Stunden erfolgen soll.


    Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.

    Control0..1
    This element is affected by the following invariants: ele-1
    BindingThe codes SHALL be taken from For codes, see Dosage Dose-Quantity ValueSet
    (required to http://ig.fhir.de/igs/medication/ValueSet/DosageDoseQuantityDE)
    TypeQuantity(SimpleQuantity), Range
    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
    Must Supporttrue
    Summarytrue
    Requirements

    The amount of therapeutic or other substance given at one administration event.

    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))

    Guidance on how to interpret the contents of this table can be foundhere

    0. Dosage
    2. Dosage.extension:generatedDosageInstructions
    Slice NamegeneratedDosageInstructions
    Control0..1
    TypeExtension(Maschinell erzeugte Dosieranweisung) (Complex Extension)
    Must Supporttrue
    4. Dosage.text
    Definition

    Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Tablette bei Bedarf'. Als Quelle dient hier ausschließlich der Arzt oder Apotheker

    ShortFreitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Tablette bei Bedarf'
    Comments

    Die Freitextdosierung sollte nur angegeben werden, wenn aufgrund der Komplexität keine strukturierte Dosierung möglich ist, um widersprüchliche Anweisungen zu vermeiden.

    Must Supporttrue
    6. Dosage.timing
    Definition

    Wann das Medikament verabreicht werden soll.

    ShortWann das Medikament verabreicht werden soll
    Comments

    Um widersprüchliche Anweisungen zu vermeiden, ist entweder Dosage.timing oder Dosage.text zu befüllen. Falls eine strukturierte Dosierung als Text abgebildet werden soll ist dafür die GeneratedDosageInstructions Extension zu verwenden.

    TypeTiming(Zeitmuster für deutschlandweite Dosierungen)
    Must Supporttrue
    8. Dosage.doseAndRate
    Definition

    Die verabreichte Menge des Medikaments.

    ShortMenge des verabreichten Medikaments
    Must Supporttrue
    10. Dosage.doseAndRate.dose[x]
    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
    SlicingThis element introduces a set of slices on Dosage.doseAndRate.dose[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
    • type @ $this
    • 12. Dosage.doseAndRate.dose[x]:doseQuantity
      Slice NamedoseQuantity
      Definition

      Menge des Medikaments pro Dosis.

      ShortMenge des Medikaments pro Dosis
      Comments

      Beachten Sie, dass dies die Menge des angegebenen Medikaments angibt, nicht die Menge für die einzelnen Wirkstoffe. Jede Wirkstoffmenge kann in der Medication-Ressource kommuniziert werden. Zum Beispiel, wenn man angeben möchte, dass eine Tablette 375 mg enthält und die Dosis eine Tablette beträgt, kann man die Medication-Ressource verwenden, um zu dokumentieren, dass die Tablette aus 375 mg des Wirkstoffs XYZ besteht. Alternativ, wenn die Dosis 375 mg beträgt, muss man möglicherweise nur angeben, dass es sich um eine Tablette handelt. Bei einer Infusion wie Dopamin, bei der 400 mg Dopamin in 500 ml einer Infusionslösung gemischt werden, würde dies alles in der Medication-Ressource kommuniziert werden. Wenn die Verabreichung nicht als sofortig vorgesehen ist (Rate ist vorhanden oder Timing hat eine Dauer), kann dies angegeben werden, um die Gesamtmenge anzugeben, die über den im Zeitplan angegebenen Zeitraum verabreicht werden soll, z. B. 500 ml in der Dosis, wobei Timing verwendet wird, um anzugeben, dass dies über 4 Stunden erfolgen soll.

      Control0..1
      BindingThe codes SHALL be taken from Dosage Dose-Quantity ValueSet
      (required to http://ig.fhir.de/igs/medication/ValueSet/DosageDoseQuantityDE)
      TypeQuantity(SimpleQuantity)
      [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
      Must Supporttrue

      Guidance on how to interpret the contents of this table can be foundhere

      0. Dosage
      Definition

      Indicates how the medication is/was taken or should be taken by the patient.

      ShortHow the medication is/was taken or should be taken
      Control0..*
      This element is affected by the following invariants: ele-1
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      2. Dosage.id
      Definition

      Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

      ShortUnique id for inter-element referencing
      Control0..1
      Typestring
      XML FormatIn the XML format, this property is represented as an attribute.
      4. Dosage.extension
      Definition

      May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

      ShortAdditional content defined by implementations
      Comments

      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

      Control0..*
      This element is affected by the following invariants: ele-1
      TypeExtension
      Standard StatusNormative (from Trial Use)
      Alternate Namesextensions, user content
      Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
      ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
      SlicingThis element introduces a set of slices on Dosage.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
      • value @ url
      • 6. Dosage.extension:generatedDosageInstructions
        Slice NamegeneratedDosageInstructions
        Definition

        Diese Extension enthält die automatisch generierte textuelle Dosierungsanweisung, die auf Basis der bereitgestellten strukturierten Dosierungsinformationen erstellt wurde.

        ShortMaschinell erzeugte Dosieranweisung
        Control0..1
        This element is affected by the following invariants: ele-1
        TypeExtension(Maschinell erzeugte Dosieranweisung) (Complex Extension)
        Must Supporttrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
        8. Dosage.modifierExtension
        Definition

        May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

        Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

        ShortExtensions that cannot be ignored even if unrecognized
        Comments

        There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

        Control0..*
        This element is affected by the following invariants: ele-1
        TypeExtension
        Is Modifiertrue because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
        Summarytrue
        Requirements

        Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

        Alternate Namesextensions, user content, modifiers
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
        10. Dosage.sequence
        Definition

        Indicates the order in which the dosage instructions should be applied or interpreted.

        ShortThe order of the dosage instructions
        Comments

        32 bit number; for values larger than this, use decimal

        Control0..1
        This element is affected by the following invariants: ele-1
        Typeinteger
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Summarytrue
        Requirements

        If the sequence number of multiple Dosages is the same, then it is implied that the instructions are to be treated as concurrent. If the sequence number is different, then the Dosages are intended to be sequential.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        12. Dosage.text
        Definition

        Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Tablette bei Bedarf'. Als Quelle dient hier ausschließlich der Arzt oder Apotheker

        ShortFreitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Tablette bei Bedarf'
        Comments

        Die Freitextdosierung sollte nur angegeben werden, wenn aufgrund der Komplexität keine strukturierte Dosierung möglich ist, um widersprüchliche Anweisungen zu vermeiden.

        Control0..1
        This element is affected by the following invariants: ele-1
        Typestring
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Must Supporttrue
        Summarytrue
        Requirements

        Free text dosage instructions can be used for cases where the instructions are too complex to code. The content of this attribute does not include the name or description of the medication. When coded instructions are present, the free text instructions may still be present for display to humans taking or administering the medication. It is expected that the text instructions will always be populated. If the dosage.timing attribute is also populated, then the dosage.text should reflect the same information as the timing. Additional information about administration or preparation of the medication should be included as text.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        14. Dosage.additionalInstruction
        Definition

        Supplemental instructions to the patient on how to take the medication (e.g. "with meals" or"take half to one hour before food") or warnings for the patient about the medication (e.g. "may cause drowsiness" or "avoid exposure of skin to direct sunlight or sunlamps").

        ShortSupplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness"
        Comments

        Information about administration or preparation of the medication (e.g. "infuse as rapidly as possibly via intraperitoneal port" or "immediately following drug x") should be populated in dosage.text.

        Control0..*
        This element is affected by the following invariants: ele-1
        BindingFor example codes, see SNOMEDCTAdditionalDosageInstructions
        (example to http://hl7.org/fhir/ValueSet/additional-instruction-codes)

        A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".

        TypeCodeableConcept
        Summarytrue
        Requirements

        Additional instruction is intended to be coded, but where no code exists, the element could include text. For example, "Swallow with plenty of water" which might or might not be coded.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        16. Dosage.patientInstruction
        Definition

        Instructions in terms that are understood by the patient or consumer.

        ShortPatient or consumer oriented instructions
        Comments

        Note that FHIR strings SHALL NOT exceed 1MB in size

        Control0..1
        This element is affected by the following invariants: ele-1
        Typestring
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        18. Dosage.timing
        Definition

        Wann das Medikament verabreicht werden soll.

        ShortWann das Medikament verabreicht werden soll
        Comments

        Um widersprüchliche Anweisungen zu vermeiden, ist entweder Dosage.timing oder Dosage.text zu befüllen. Falls eine strukturierte Dosierung als Text abgebildet werden soll ist dafür die GeneratedDosageInstructions Extension zu verwenden.

        Control0..1
        This element is affected by the following invariants: ele-1
        TypeTiming(Zeitmuster für deutschlandweite Dosierungen)
        Must Supporttrue
        Summarytrue
        Requirements

        The timing schedule for giving the medication to the patient. This data type allows many different expressions. For example: "Every 8 hours"; "Three times a day"; "1/2 an hour before breakfast for 10 days from 23-Dec 2011:"; "15 Oct 2013, 17 Oct 2013 and 1 Nov 2013". Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        20. Dosage.asNeeded[x]
        Definition

        Indicates whether the Medication is only taken when needed within a specific dosing schedule (Boolean option), or it indicates the precondition for taking the Medication (CodeableConcept).

        ShortTake "as needed" (for x)
        Comments

        Can express "as needed" without a reason by setting the Boolean = True. In this case the CodeableConcept is not populated. Or you can express "as needed" with a reason by including the CodeableConcept. In this case the Boolean is assumed to be True. If you set the Boolean to False, then the dose is given according to the schedule and is not "prn" or "as needed".

        Control0..1
        This element is affected by the following invariants: ele-1
        BindingFor example codes, see SNOMEDCTMedicationAsNeededReasonCodes
        (example to http://hl7.org/fhir/ValueSet/medication-as-needed-reason)

        A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.

        TypeChoice of: boolean, CodeableConcept
        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        22. Dosage.site
        Definition

        Body site to administer to.

        ShortBody site to administer to
        Comments

        If the use case requires attributes from the BodySite resource (e.g. to identify and track separately) then use the standard extension bodySite. May be a summary code, or a reference to a very precise definition of the location, or both.

        Control0..1
        This element is affected by the following invariants: ele-1
        BindingFor example codes, see SNOMEDCTAnatomicalStructureForAdministrationSiteCodes
        (example to http://hl7.org/fhir/ValueSet/approach-site-codes)

        A coded concept describing the site location the medicine enters into or onto the body.

        TypeCodeableConcept
        Summarytrue
        Requirements

        A coded specification of the anatomic site where the medication first enters the body.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        24. Dosage.route
        Definition

        How drug should enter body.

        ShortHow drug should enter body
        Comments

        Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.

        Control0..1
        This element is affected by the following invariants: ele-1
        BindingFor example codes, see SNOMEDCTRouteCodes
        (example to http://hl7.org/fhir/ValueSet/route-codes)

        A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.

        TypeCodeableConcept
        Summarytrue
        Requirements

        A code specifying the route or physiological path of administration of a therapeutic agent into or onto a patient's body.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        26. Dosage.method
        Definition

        Technique for administering medication.

        ShortTechnique for administering medication
        Comments

        Terminologies used often pre-coordinate this term with the route and or form of administration.

        Control0..1
        This element is affected by the following invariants: ele-1
        BindingFor example codes, see SNOMEDCTAdministrationMethodCodes
        (example to http://hl7.org/fhir/ValueSet/administration-method-codes)

        A coded concept describing the technique by which the medicine is administered.

        TypeCodeableConcept
        Summarytrue
        Requirements

        A coded value indicating the method by which the medication is introduced into or onto the body. Most commonly used for injections. For examples, Slow Push; Deep IV.

        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        28. Dosage.doseAndRate
        Definition

        Die verabreichte Menge des Medikaments.

        ShortMenge des verabreichten Medikaments
        Control0..*
        This element is affected by the following invariants: ele-1
        TypeElement
        Must Supporttrue
        Summarytrue
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        30. Dosage.doseAndRate.id
        Definition

        Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

        ShortUnique id for inter-element referencing
        Control0..1
        Typestring
        XML FormatIn the XML format, this property is represented as an attribute.
        32. Dosage.doseAndRate.extension
        Definition

        May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

        ShortAdditional content defined by implementations
        Comments

        There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

        Control0..*
        This element is affected by the following invariants: ele-1
        TypeExtension
        Standard StatusNormative (from Trial Use)
        Alternate Namesextensions, user content
        Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
        ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
        SlicingThis element introduces a set of slices on Dosage.doseAndRate.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
        • value @ url
        • 34. Dosage.doseAndRate.type
          Definition

          The kind of dose or rate specified, for example, ordered or calculated.

          ShortThe kind of dose or rate specified
          Comments

          Not all terminology uses fit this general pattern. In some cases, models should not use CodeableConcept and use Coding directly and provide their own structure for managing text, codings, translations and the relationship between elements and pre- and post-coordination.

          Control0..1
          This element is affected by the following invariants: ele-1
          BindingFor example codes, see DoseAndRateType
          (example to http://hl7.org/fhir/ValueSet/dose-rate-type)

          The kind of dose or rate specified.

          TypeCodeableConcept
          Summarytrue
          Requirements

          If the type is not populated, assume to be "ordered".

          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          36. Dosage.doseAndRate.dose[x]
          Definition

          Amount of medication per dose.

          ShortAmount of medication per dose
          Comments

          Note that this specifies the quantity of the specified medication, not the quantity for each active ingredient(s). Each ingredient amount can be communicated in the Medication resource. For example, if one wants to communicate that a tablet was 375 mg, where the dose was one tablet, you can use the Medication resource to document that the tablet was comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only need to use the Medication resource to indicate this was a tablet. If the example were an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed in 500 ml of some IV solution, then this would all be communicated in the Medication resource. If the administration is not intended to be instantaneous (rate is present or timing has a duration), this can be specified to convey the total amount to be administered over the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used to convey that this should be done over 4 hours.

          Control0..1
          This element is affected by the following invariants: ele-1
          TypeChoice of: Range, Quantity(SimpleQuantity)
          [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
          Summarytrue
          Requirements

          The amount of therapeutic or other substance given at one administration event.

          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
          SlicingThis element introduces a set of slices on Dosage.doseAndRate.dose[x]. The slices areUnordered and Open, and can be differentiated using the following discriminators:
          • type @ $this
          • 38. Dosage.doseAndRate.dose[x]:doseQuantity
            Slice NamedoseQuantity
            Definition

            Menge des Medikaments pro Dosis.

            ShortMenge des Medikaments pro Dosis
            Comments

            Beachten Sie, dass dies die Menge des angegebenen Medikaments angibt, nicht die Menge für die einzelnen Wirkstoffe. Jede Wirkstoffmenge kann in der Medication-Ressource kommuniziert werden. Zum Beispiel, wenn man angeben möchte, dass eine Tablette 375 mg enthält und die Dosis eine Tablette beträgt, kann man die Medication-Ressource verwenden, um zu dokumentieren, dass die Tablette aus 375 mg des Wirkstoffs XYZ besteht. Alternativ, wenn die Dosis 375 mg beträgt, muss man möglicherweise nur angeben, dass es sich um eine Tablette handelt. Bei einer Infusion wie Dopamin, bei der 400 mg Dopamin in 500 ml einer Infusionslösung gemischt werden, würde dies alles in der Medication-Ressource kommuniziert werden. Wenn die Verabreichung nicht als sofortig vorgesehen ist (Rate ist vorhanden oder Timing hat eine Dauer), kann dies angegeben werden, um die Gesamtmenge anzugeben, die über den im Zeitplan angegebenen Zeitraum verabreicht werden soll, z. B. 500 ml in der Dosis, wobei Timing verwendet wird, um anzugeben, dass dies über 4 Stunden erfolgen soll.

            Control0..1
            This element is affected by the following invariants: ele-1
            BindingThe codes SHALL be taken from Dosage Dose-Quantity ValueSet
            (required to http://ig.fhir.de/igs/medication/ValueSet/DosageDoseQuantityDE)
            TypeQuantity(SimpleQuantity)
            [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
            Must Supporttrue
            Summarytrue
            Requirements

            The amount of therapeutic or other substance given at one administration event.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            40. Dosage.doseAndRate.rate[x]
            Definition

            Amount of medication per unit of time.

            ShortAmount of medication per unit of time
            Comments

            It is possible to supply both a rate and a doseQuantity to provide full details about how the medication is to be administered and supplied. If the rate is intended to change over time, depending on local rules/regulations, each change should be captured as a new version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest with the new rate.

            It is possible to specify a rate over time (for example, 100 ml/hour) using either the rateRatio and rateQuantity. The rateQuantity approach requires systems to have the capability to parse UCUM grammer where ml/hour is included rather than a specific ratio where the time is specified as the denominator. Where a rate such as 500ml over 2 hours is specified, the use of rateRatio may be more semantically correct than specifying using a rateQuantity of 250 mg/hour.

            Control0..1
            This element is affected by the following invariants: ele-1
            TypeChoice of: Ratio, Range, Quantity(SimpleQuantity)
            [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
            Summarytrue
            Requirements

            Identifies the speed with which the medication was or will be introduced into the patient. Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr. May also be expressed as a rate per unit of time e.g. 500 ml per 2 hours. Other examples: 200 mcg/min or 200 mcg/1 minute; 1 liter/8 hours. Sometimes, a rate can imply duration when expressed as total volume / duration (e.g. 500mL/2 hours implies a duration of 2 hours). However, when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is needed to convey the infuse over time period.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            42. Dosage.maxDosePerPeriod
            Definition

            Upper limit on medication per unit of time.

            ShortUpper limit on medication per unit of time
            Comments

            This is intended for use as an adjunct to the dosage when there is an upper cap. For example "2 tablets every 4 hours to a maximum of 8/day".

            Control0..1
            This element is affected by the following invariants: ele-1
            TypeRatio
            Summarytrue
            Requirements

            The maximum total quantity of a therapeutic substance that may be administered to a subject over the period of time. For example, 1000mg in 24 hours.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            rat-1: Numerator and denominator SHALL both be present, or both are absent. If both are absent, there SHALL be some extension present ((numerator.empty() xor denominator.exists()) and (numerator.exists() or extension.exists()))
            44. Dosage.maxDosePerAdministration
            Definition

            Upper limit on medication per administration.

            ShortUpper limit on medication per administration
            Comments

            This is intended for use as an adjunct to the dosage when there is an upper cap. For example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum 2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration of 2 mg.

            Control0..1
            This element is affected by the following invariants: ele-1
            TypeQuantity(SimpleQuantity)
            Is Modifierfalse
            Summarytrue
            Requirements

            The maximum total quantity of a therapeutic substance that may be administered to a subject per administration.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            qty-3: If a code for the unit is present, the system SHALL also be present (code.empty() or system.exists())
            sqty-1: The comparator is not used on a SimpleQuantity (comparator.empty())
            46. Dosage.maxDosePerLifetime
            Definition

            Upper limit on medication per lifetime of the patient.

            ShortUpper limit on medication per lifetime of the patient
            Comments

            The context of use may frequently define what kind of quantity this is and therefore what kind of units can be used. The context of use may also restrict the values for the comparator.

            Control0..1
            This element is affected by the following invariants: ele-1
            TypeQuantity(SimpleQuantity)
            Is Modifierfalse
            Summarytrue
            Requirements

            The maximum total quantity of a therapeutic substance that may be administered per lifetime of the subject.

            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
            qty-3: If a code for the unit is present, the system SHALL also be present (code.empty() or system.exists())
            sqty-1: The comparator is not used on a SimpleQuantity (comparator.empty())